dendrobium officinale kimura et migo

We evaluated the therapeutic potential of DO in treating diabetic nephropathy (DN) by preventing insulin resistance. Due to the special trophic mode, seed germination of Dendrobium officinale needs the root symbiotic bacteria [87, 88]; the reproduction of wild Dendrobium officinale is limited with low natural reproductive rates. Modern pharmacology research has confirmed that Dendrobium officinale and its polysaccharide fraction possess anticancer, hepatoprotective, hypolipidemic, antifatigue, antioxidant, anticonstipation, hypoglycemic, gastric ulcer protective, and antihypertensive effects, immunoenhancement, and so on [2–4]. Erianin significantly inhibited the proliferation of HepG2 and Huh7 (human hepatoma cell lines) in vitro [38] and also prevented angiogenesis in human hepatoma Be17402 and human melanoma A375 in vivo [39]. Dendrobium officinale Kimura et Migo (D. officinale) is a famous traditional Chinese medicine (TCM). Patents and health care products were also improved by the combination of production and research mode. DOI: 10.12659/MSMBR.909242. Front Bioeng Biotechnol. As reported, the alkaloid in Dendrobium officinale belongs to the terpenoid indole alkaloid (TIA) class, with its total content measured at approximately 0.02% [49]. China Dried Flower of Dendrobium Candidum, Find details about China Flower of Dendrobium Candidum, Flower of Dendrobium Officinale Kimura Et Migo from Dried Flower of Dendrobium Candidum - Hangzhou Excelente Chemicals Co., Ltd. Dendrobii Officinalis Caulis, the stems of Dendrobium officinale Kimura et Migo, as a tonic herb in Chinese materia medica and health food in folk, has been utilized for the treatment of yin-deficiency diseases for decades. The past three decades witnessed excess herb-gathering of Dendrobium officinale destroying much of the wild habitat resource in China [89]. It is apparent that Dendrobium officinale germplasm resources’ separation and purification determine its characters and quality [94]. It is found that Dendrobium officinale had hypolipidemic and hypotensive effects. Liu JJ, Shentu LM, Ma N, Wang LY, Zhang GM, Sun Y, Wang Y, Li J, Mu YL. The average content of neutral sugar in desiccated Dendrobium officinale is up to 58.3% [26]. Wang XT, Gong Y, Zhou B, Yang JJ, Cheng Y, Zhao JG, Qi MY. From Dendrobium officinale, nine phenanthrenes (1–9) were isolated. Oral administration of DOP decreased levels of fasting blood glucose (FBG) and glycosylated serum protein (GSP) and increased level of serum insulin in alloxan-induced diabetic mice. The anticancer activity of Dendrobium officinale extract has been studied and proved, such as anti-HelaS3, anti-HepG2, and anti-HCT-116 in vitro, as well as anti-CNEl and CNE2 in vivo and in vitro [69]. The hepatoprotective capacity of Dendrobium officinale is always related to its antioxidant ability, especially in acute or chronic alcoholic liver injury. In contrast to the extensive genomic and transcriptomic resources generated in this medicinal species, detailed metabolomic data are still missing. Over the past decades, about 190 compounds have been isolated from Dendrobium officinale Kimura et Migo. Biomed Pharmacother.  |  Dendrobium officinale Kimura et Migo: A Review on Its Ethnopharmacology, Phytochemistry, Pharmacology, and Industrialization Table 1 The taxonomic classification, names, and distribution of Dendrobium officinale Kimura et Migo. Kimura et Migo (Orchidaceae family) is a prized traditional Chinese medicine, which has been used clinically to promote body fluid production and maintain gastric tonicity in China and Southeast Asia(8). Dendrobium officinale Kimura et Migo (Dendrobium catenatum Lindley), a functional food and medicine herbal, has shown great pharmacological activity on diabetes and hypertension. Ming Zhao, Jungang Han. 2018 Jan;97:1461-1467. doi: 10.1016/j.biopha.2017.11.032. This concentration (200 mg/kg) had the strongest inhibitory effect of gastric injury (76.6% inhibition of gastric injury rate) [75]. After acute toxicity test, genetic toxicity test (Ames test, micronucleus test of bone marrow, and sperm shape abnormality test in mice) and 90-day feeding test in rats, the results showed that protocorms of Dendrobium officinale were without toxicity, genetic toxicity and mutagenicity within the scope of the test dose [84]. This Latin name was firstly denominated by two Japanese scholars in 1936 when they found the new species of Dendrobium in China [12]. Rapid propagation technology has gradually matured, so yield is no longer the bottleneck of Dendrobium officinale development. Reference page. Methods. As precious medicinal materials, maybe the high price limits the application of tiepishihu. Dendrobium aurantiacum Rchb.f. The fine powder solution of Dendrobium officinale (1.5, 3 g/kg) can reduce the levels of TG, TCHOL, and LDL-C in serum significantly and reduce the expression of TNF-α and IL-6 in ApoE−/− mice. Accessed: 2019 April 29. Conclusions. B. Hu, Z. R. Zheng et al., “Preliminary study on the DNA barcoding in Dendrobium officinale germplasm resources,”, X. M. Chen, C. L. Wang, J. S. Yang, and S. X. Guo, “Research progress on chemical composition and chemical analysis of Dendrobium officinale,”, Z. C. Zhang, J. Some friends grow dendrobium, after a period of … Finally, industrialization will drive further researches and is conducive to develop deep-processing products, especially the insufficient new drugs, which will also promote the industrialization and form a virtuous circle simultaneously (Figure 3). Combined with modern medicine, Dendrobium officinale can be used to treat many diseases including Sjögren’s syndrome, gastric ulcer, alcoholic liver injury, chronic obstructive pulmonary disease, diabetes, obesity, rheumatoid arthritis, hypertensive stroke, cataract, weak constitution, or subhealth [2, 20–22]. B. Yi, and J. J. Li, “Advances in the study of polysaccharide from Dendrobium officinale,”, Q. Li, Y. Xie, J. Su, Q. Ye, and Z. Jia, “Isolation and structural characterization of a neutral polysaccharide from the stems of Dendrobium densiflorum,”, X. Xing, S. W. Cui, S. Nie, G. O. Phillips, H. Douglas Goff, and Q. Wang, “A review of isolation process, structural characteristics, and bioactivities of water-soluble polysaccharides from, X. Xing, S. W. Cui, S. Nie, G. O. Phillips, H. D. Goff, and Q. Wang, “Study on Dendrobium officinale O-acetyl-glucomannan (Dendronan®): part II. A. Teixeira da Silva, X. Jin, J. Dobránszki et al., “Advances in Dendrobium molecular research: applications in genetic variation, identification and breeding,”, Y. Y. Xiao, J. Y. Weng, and J. S. Fan, “Pharmacognosy identification of Dendrobium officinale and Dendrobium devonianum,”, Y. H. Bao, C. M. Pan, and Y. Bai, “Comprehensive analysis of identification characters of three medicinal dendrobii,”, J. Shen, X. Ding, D. Liu et al., “Intersimple sequence repeats (ISSR) molecular fingerprinting markers for authenticating populations of, S. Feng, R. He, S. Yang et al., “Start codon targeted (SCoT) and target region amplification polymorphism (TRAP) for evaluating the genetic relationship of Dendrobium species,”, S. G. Feng, J. J. Lu, L. Gao, J. J. Liu, and H. Z. Wang, “Molecular phylogeny analysis and species identification of Dendrobium (Orchidaceae) in China,”. There are 1 OEM, 2 ODM, 2 Self Patent. He, Y. P. Huang, L. Yang et al., “Structural characterization and immunomodulating activity of polysaccharide from, M. Q. Huang, B. H. Huang, T. Y. Cai, Q. L. Liu, D. Li, and A. A mixture of D. officinale and American ginseng has been shown to enhance cell-mediated immunity, humoral immunity, and monocyte/macrophage functions in mice. However, gastric ulcer is a chronic disease, the security of long-term administration of Dendrobium officinale still uncertain. Dendrobium nobile extract have function of ziyin Ikitsu This site needs JavaScript to work properly. Dendrobium officinale Kimura et Migo: A Review on Its Ethnopharmacology, Phytochemistry, Pharmacology, and Industrialization. Why don’t dendrobium grow roots. (1) Polysaccharides are the main composition in Dendrobium officinale with numerous pharmacological researches, but investigation related to its structure-activity relationships remains scant. T. T. Rui, Yunnan has completed Dendrobium officinale's fine gene map, which will push the province's Dendrobium industry. What is more, in 2010 ChP, tiepishihu was initially isolated as one single medicine; its processed stem was called Dendrobii Officinalis Caulis (valid botanical name: Dendrobium catenatum Lindl., taxonomic classification and synonyms in Table 1); in the meanwhile, Dendrobium nobile Lindl., Dendrobium chrysotoxum Lindl., Dendrobium fimbriatum Hook., and their similar species were collectively referred to as shihu [13]. Physicochemical and Antioxidant Properties of the Degradations of Polysaccharides from, Anti-Diabetic Effect of a Shihunine-Rich Extract of, NCI CPTC Antibody Characterization Program. Fourier Transform Infrared Spectrometer (FT-IR), Gas Chromatography-Mass Spectrometer (GC-MS), and 1H and 13C NMR spectroscopies have been used to analyze the types of monosaccharide residues and the linkage sites of glycosidic bonds [32]. The taxonomic classification, names, and distribution of, Some chemical structure of compounds isolated form, Zhejiang Chinese Medical University, 548 Binwen Rd., Binjiang District, Hangzhou, China, Evidence-Based Complementary and Alternative Medicine, Species 2000 & ITIS Catalogue of Life: Plantae > Tracheophyta > Liliopsida > Asparagales > Orchidaceae > Dendrobium >, IUCN Red List: Plantae > Tracheophyta > Liliopsida > Orchidales > Orchidaceae > Dendrobium >, NCBI Taxonomy: Eukaryota > Viridiplantae > Streptophyta > Streptophytina > Embryophyta > Tracheophyta > Euphyllophyta > Spermatophyta > Magnoliophyta > Mesangiospermae > Liliopsida > Petrosaviidae > Asparagales > Orchidaceae > Epidendroideae > Epidendroideae incertae sedis > Dendrobiinae > Dendrobium >, Taxonomic Hierarchy of COL-China 2012: Plantae > Angiospermae > Monocotyledoneae > Microspermae > Orchidaceae > Dendrobium >, Tropicos resource: Equisetopsida C. Agardh > Asparagales Link > Orchidaceae Juss. In terms of microscopic identification, Dendrobium officinale could be identified by vascular bundle sheath observed under the fluorescence microscopy and the distribution of raphides under normal light microscopy [95]. D. officinale protocorms (DOPs) are the conical embryonic tissues formed after seed germination. Find high quality Dendrobium Officinale Kimura Et Migo Suppliers on Alibaba. Tìm kiếm nhân giống invitro dendrobium officinale kimura et migo , nhan giong invitro dendrobium officinale kimura et migo tại 123doc - Thư viện trực tuyến hàng đầu Việt Nam Dendrobium officinale containing a high content of (E)-2-hexenal (106) shows bactericidal activity against Pseudococcus viburni, Pseudococcus affinis, Bemisia sp., and Frankliniella occidentalis [46]. The present study was aimed to investigate the effects and the possible mechanisms of the Dendrobium officinale extracts (DOE) on diabetic cardiomyopathy in mice. After 8 weeks treatment of DOE, mice were sacrificed, blood sample and heart tissues were collected. Zhang X, Luo Y, Wei G, Li Y, Huang Y, Huang J, Liu C, Huang R, Liu G, Wei Z, Du S. Evid Based Complement Alternat Med. (3) There is no enough systemic data about toxicology of Dendrobium officinale. Today, Dendrobium officinale Kimura et Migo Extract powder is showing up in preworkout supplements used to boost physical and athletic performance. Dendrobium, pertaining to the second largest family, Orchidaceae, includes approximately l,400 species worldwide distributed from tropical Asia to Oceania [6]. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Consequently, the following points deserve further investigation. Extraction and quantitative and qualitative analysis are described as follows, and the pharmacological effects of polysaccharides are in Table 3. Links . In addition, Western blot detection and analysis showed that DOE down-regulated the expression of TGF-β, collegan-1, fibronectin, NF-κB, TNF-α and IL-1β. In 2010 ChP, tiepishihu was renamed as Dendrobium officinale Kimura et Migo (aka Dendrobium officinale, Figure 1(a)). Ethnopharmacological Relevance. This may mainly attribute to the major and bioactive components: polysaccharides. Dendrobium officinale Kimura et Migo is a commercially and pharmacologically highly prized species widely used in Western Asian countries. Dendrobium Officinale Kimura Et Migo Plant For Sale - Hello friend Orchid Flowers, In the article that you read this time with the title Dendrobium Officinale Kimura Et Migo Plant For Sale, we have prepared this article well for you to read and take information in it. B. Zhao, and G. X. Cai, “Advances in the of resources, constituents and pharmacological effects of Dendrobium officinale,”, G. Y. Lü, S. H. Chen, L. D. Zhang et al., “Dendrobium officinale effect on two kinds of serum transaminases and cholesterol of mice model with chronic alcoholic liver injury,”, X. H. Tang, S. H. Chen, G. Y. Lü, J. Su, and M. C. Huang, “Effects of Dendrobium Candidum on SOD, MDA and GSH-Px in mice model of acute alcoholic hepatic injury,”, Y. H. Ge, J. Wang, F. Yang, G. H. Dai, and Y. L. Tong, “Effects of fresh Dendrobium officinale polysaccharides on immune function in mice with Lewis lung cancer,”, L. H. Pan, X. F. Li, M. N. Wang et al., “Comparison of hypoglycemic and antioxidative effects of polysaccharides from four different dendrobium species,”, H. S. Wu, J. H. Xu, L. Z. Chen, and J. J. Dendrobium officinale contains a kind of bibenzyl and a kind of phenanthrene identified in D. chrysotoxum before: chrysotobibenzyl (11) and erianin (6). Among them, Dictamnoside A (80) showed immunomodulatory activity in mouse splenocyte assessed as stimulation of proliferation at 10 umole/L after 44 hours by MTT assay in the presence of Concanavalin A (ConA) [43]. NIH Curr Med Sci. Intragastric administration of SD rats with 200 mg/kg of Dendrobium officinale for two weeks decreased gastric secretion, IL-6 and TNF-α cytokine levels compared with the lower dose groups and the control groups. Epub 2018 Oct 10. 81573700), Zhejiang Provincial Natural Science Foundation of China (no. In addition, DOP attenuated the occurrence of oxidative stress in the liver and kidney of alloxan-induced diabetic mice by decreasing MDA levels, increasing GSH concentrations and antioxidative enzyme activities [70]. A. Miller, K. Pappan, P. A. Thompson et al., “Plasma metabolomic profiles of breast cancer patients after short-term limonene intervention,”, D. G. Hammond, S. Rangel, and I. Kubo, “Volatile aldehydes are promising broad-spectrum postharvest insecticides,”, S. K. Suzuki, “Study on Chinese Flickingeria alkaloids (Dendrobium Alkaloids research,”, S. Li, C. L. Wang, and S. X. Guo, “Determination of dendrobin in dendrobium nobile by HPLC analysis,”, X. Guo, Y. Li, C. Li et al., “Analysis of the Dendrobium officinale transcriptome reveals putative alkaloid biosynthetic genes and genetic markers,”, H. Asahina, J. K. Shinozaki, K. Masuda, Y. Morimitsu, and M. Satake, “Identification of medicinal, Z. Q. Yuan, J. Y. Zhang, and T. Liu, “Phylogenetic relationship of China Dendrobium species based on the sequence of the internal transcribed spacer of ribosomal DNA,”, R. S. Li, X. Yang, P. He, and N. Gan, “Studies on phenanthrene constituents from stems of, Q. Xu, S. H. Chen, and G. Y. Lü, “Pharmacological research progress of the three constituents of different Dendrobium,”, Y. Li, C. L. Wang, S. X. Guo, J. S. Yang, and P. G. Xiao, “Two new compounds from Dendrobium candidum,”, Y. Li, C. L. Wang, F. F. Wang et al., “Phenolic components and flavanones from Dendrobium candidum,”, Z. Y. Wei, J. J. Lu, C. S. Jin, and H. Xia, “Chemical constituents from n-butanol extracts of Dendrobium officinale,”, F. F. Wang, Y. Li, H. L. Dong, S. X. Guo, C. L. Wang, and J. S. Yang, “A new compound from Dendrobium candidum,”, J. Li, S. X. Li, D. Huang, X. S. Z. Hou, S. Huang, Y. M. Liang et al., “The medicinal use of Dendrobium officinale,” China Patent CN102552698A, 2012. Meanwhile, research showed that the DOP group demonstrated higher average scores and an improved average quality of hair growth of C57BL/6J mice (5.0 g/L, the solution was ultra-pure water, each 0.2 mL, smeared for 21 d), compared with the control group. Advances in the Application of Biomimetic Endometrium Interfaces for Uterine Bioengineering in Female Infertility. The stems of Dendrobium officinale are mainly used as health food in folk. Dendrobium officinale exhibited a significant hypoglycemic effect in adrenaline hyperglycemia mice and streptozotocin-diabetic (STZ-DM) rats [71]. Evid Based Complement Alternat Med. Evid Based Complement Alternat Med. All rights reserved. 2020 Feb 28;8:153. doi: 10.3389/fbioe.2020.00153. However, TCM physicians use shihu more frequently than tiepishihu. In addition, it could reduce areas of atheromatous plaque in aortic valve and arch in ApoE−/− mice and then decrease the expression of TNF-α and IL-6 in aortic arch [77]. DCET-18 (35) also inhibited the migratory behavior and induced the apoptosis of non-small-cell lung cancer cells (human NCI-H460 cells) [42]. תמצית Dendrobium officinale Kimura et Migo. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Research showed that two DOP fractions, DOP-1 and DOP-2, promoted splenocyte proliferation, enhanced NK cell-mediated cytotoxicity, and increased the phagocytosis and nitric oxide production of macrophages significantly () [82]. Toxicol Mech Methods. In recent years, the development of Dendrobium officinale health care products is promising [15]. 2020;43(5):864-872. doi: 10.1248/bpb.b19-01073. Hanxiao Tang, Tianwen Zhao, Yunjie Sheng, Ting Zheng, Lingzhu Fu, Yongsheng Zhang, "Dendrobium officinale Kimura et Migo: A Review on Its Ethnopharmacology, Phytochemistry, Pharmacology, and Industrialization", Evidence-Based Complementary and Alternative Medicine, vol. 1,5-Dicarboxy-1,2,3,4-tetramethoxyphenanthrene, 2,4,7-Trihydroxy-9,10-dihydrophenanthrene, 4-(4-Hydroxyphenethyl)-2,6-dimethoxyphenol, 4-(4-Hydroxy-3-methoxyphenethyl)-2,6-dimethoxyphenol, Cis-3-(4-Hydroxy-3-methoxy-phenyl)-acrylic acid octacosyl ester, Trans-3-(4-Hydroxy-3-methoxy-phenyl)-acrylic acid octacosyl ester, 4-[2-(4-Methoxy-phenyl)-ethyl-6]-oxo-6H-pyran-2-carboxylic acid methyl ester, 4-Hydroxy-N-[2-(4-hydroxyphenyl)ethyl]benzenepropanamide, (1′R)-1′-(4-Hydroxy-3,5-dimethoxylphenyl) propan-1′-ol 4-O-, 2,6-Dimethoxycyclohexa-2,5-diene-1,4-dione, 3-Ethoxy-5-hydroxy-7-methoxy-1,4-phenanthra-quinone, Arabinose : mannose : glucose : galactose = 1.26 : 4.05 : 32.05 : 3.67, Decreased mice serum ALT, AST, ALP activity, and TBIL levels; increased serum HDL-C; decreased LDL-C levels; accelerated metabolism of serum TG and TC; increased liver ADH, ALDH activities; inhibited mRNA expression of P4502E1, TNF-, Increased GR activity and GSH-Px activity in mice, Reduced chronic alcoholic liver injured mice’s serum ALT, AST, and TC levels, Increased acute alcoholic hepatic injured mice’s SOD of serum and liver and DSG-Px of liver, Water extraction by alcohol sedimentation, extraction rate (in dry herb): 19.2%, Increased the level of carbon clearance indexes and NK cells activity of LLC mice (, Improved the LLC mice’s spleen lymphocyte transformation and hemolysin levels (, Water extraction by alcohol sedimentation, Inhibited the growth of human hepatoma cells (HepG2), human lung cancer cells (A549), and human teratoma stem cells (NCCIT), Inhibited murine teratoma stem cells (F9) and promoted their apoptosis, Promoted the proliferation of mouse spleen cells, Water extraction and alcohol precipitation, Inhibited the growth transplantation tumor (CNE1 and CNE2) of NPC nude mice, Inhibited the proliferation and induced the apoptosis of CNE1 and CNE2 cells; activated caspase-3; declined Bcl-xL, Mcl-1 protein levels, DOP: 2-O-acetylglucomannan consisted of Man, Glc, and Ara in the molar ratio of 40.2 : 8.4 : 1.0, Decreased levels of fasting blood glucose (FBG) and glycosylated serum protein (GSP); increased level of serum insulin in alloxan induced diabetic mice; attenuated the occurrence of oxidative stress in the liver and kidney of alloxan-induced diabetic mice (decreased MDA levels; increased GSH concentrations and antioxidative enzyme activities), Reduced STZ-DM rats’ blood glucose and glucagon levels; enhanced the number of islet, Decreased blood glucose and increased liver glycogen content in adrenaline induced hyperglycemia rats, Total polysaccharide: 43.1%, total flavonoids: 19.6%, crude drug 1 g/mL, TP (total polysaccharides, 100 mg/kg), TF (total flavonoids, 35 mg/kg), and TE (water extract, 6 g/kg), Significantly downregulated the phosphorylation of JNK (Thr, Hot water reflux and cellulase lixiviating extraction, Increased mice’s glycogen store after exercise fatigue, Decreased the level of serum urea and lactic acid accumulation; upregulated the expression of CNTF mRNA in mice, Increased carbon clearance indexes from 0.025 to 0.034 in mice, Extended burden swimming time of mice; reduced serum lactic acids of mice, Lyophilization then hot-water extraction, evaporation, Decreased SD rats’ gastric secretion, IL-6, and TNF-, Declined irritable and chemical gastric ulcer model’s ulcer indexes in mice, Extended Stroke-prone spontaneously hypertensive (SHR-sp) rats’ blood pressure, living days, and survival rate, Water extraction by alcohol sedimentation; mannose : glucose : galactose : arabinose : xylose : glucuronic acid = 10 : 0.25 : 1.2 : 4.7 : 1.3 : 1.4, Inhibited Bax/Bal-2 ratio and caspase-3 expression; decreased expression of cytokines (TNF-, Ameliorated the abnormalities of aquaporin-5 (AQP-5) on A-253 cell, Water extract and alcohol precipitate, extraction rate: 29.87%, Increased average score and average quality of hair growth of C57BL/6J mice, Increased HaCaT cells survival rate and the VEGF mRNA expression level, Dry power decoction then concentration: traditional decoction or dry power steep in hot water: ultra-fine powder decoction, Increased Shannon index and Brillouin index in mice with constipation and improved their molecular diversity of intestinal, Convention of International Trade in Endangered Species of Wild Fauna and Flora, 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium  bromide, G. Y. Lü, M. Q. Yan, and S. H. Chen, “Review of pharmacological activities of, Q. L. Luo, Z. H. Tang, X. F. Zhang et al., “Chemical properties and antioxidant activity of a water-soluble polysaccharide from, T. B. 2018 Dec;108:1640-1650. doi: 10.1016/j.biopha.2018.10.026. Epub 2017 Mar 12. Research and Development Department, Shanghai Sanxiang Investment holdings Co., Ltd., Shanghai, China (mainland) Med Sci Monit Basic Res 2018; 24:84-92. Research showed that polysaccharides distributing in different parts of Dendrobium officinale varied: middle stem > upper stem > lower stem > roots [31]. Dendrobium fimbriatum Hook Picture. Evidence-Based Complementary and Alternative Medicine, Mar 2017 Actually, different production origins, processing methods, growing years, and cultivated or wild and different parts of Dendrobium officinale are all related to polysaccharide content. using pressurized liquid extraction and ultra-performance liquid chromatography,”, X. Jin and L. Huang, “(2352) Proposal to conserve the name Dendrobium officinale against D. stricklandianum, D. tosaense, and D. pere-fauriei (Orchidaceae),”, X. G. Xiang, A. Schuiteman, D. Z. Li et al., “Molecular systematics of Dendrobium (Orchidaceae, Dendrobieae) from mainland Asia based on plastid and nuclear sequences,”, P. Hao, L. Guo, L. Xu et al., “Study on HPLC fingerprint in different species of Dendrobii Caulis,”, G. X. Cai, J. Li, S. X. Li, D. Huang, and X. Dendrobium findlayanum Par. Et Rchb. 2020-06-14 | 0 Comment. The proven health benefits of dendrobium officinale kimura et migo … Background Dendrobium officinale Kimura et Migo, a member of the genus Dendrobium, is a traditional Chinese medicine with high commercial value. Pretreatment with DOE decreased the heart-to-body weight ratio (HW/BW) and showed an evident hypoglycemic effect. In addition, the taxonomy, phylogeny, and breeding of Dendrobium species have made great progress as the advance of molecular markers in the past two decades [96]. The role of zinc in the prevention of diabetic cardiomyopathy and nephropathy. Research showed that Dendrobium officinale had a preventive effect of gastric injury caused by 60% ethanol-hydrochloric acid solution (ethanol was dissolved in 150 mM hydrochloric acid). Govaerts, R. et al. In the last few decades, at least 26 saccharides and glycosides have been found from Dendrobium officinale, (compounds 63–88). Dendrobium officinale, one of the most famous species of Dendrobium, has long been regarded as precious herbs and health foods applied in TCM and in folk. Generally, there are three methods that can isolate crude Dendrobium officinale polysaccharides (DOP): a solvent method (water extraction by alcohol sedimentation), a biological method (enzyme extraction), and a physical method (ultrasonic extraction and microwave extraction). Compounds 89–172, isolated from Dendrobium officinale, comprise essential oils. B. Zhao, “Applications of dendrobium officinale in ancient and modern times,”, S. H. Chen, M. Q. Yan, G. Y. Lü, and X. Liu, “Development of dendrobium officinale kimura et migo related health foods,”, M. J. Yang, P. Yu, L. D. Lu, Z. M. Lü, and X. X. Chen, “Effects of dendrobium candicum capsules on immune responses in mouse,”, J. Wang and B. C. Wang, “Fresh Dendrobium officinale clinic applications,”, C. Huang, D. Wang, L. Sun, and L. Wei, “Effects of exogenous salicylic acid on the physiological characteristics of dendrobium officinale under chilling stress,”, S. Z. Hou, C. Y. Liang, H. Z. Liu et al., “, T. H. Song, X. X. Chen, S. C. W. Tang et al., “Dendrobium officinale polysaccharides ameliorated pulmonary function while inhibiting mucin-5AC and stimulating aquaporin-5 expression,”, Y. Y. Ye, “Ultrasonic extraction research on polysaccharides of Dendrobium officinale,”, S. H. Bao, X. Q. Cha, J. Hao, and J. P. Luo, “Studies on antioxidant activity of polysaccharides from dendrobium candidum in vitro,”, M. Y. Xie and S. P. Nie, “Research progress of natural polysaccharides' structure and function,”, X. Xing, S. W. Cui, S. Nie, G. O. Phillips, H. D. Goff, and Q. Wang, “Study on Dendrobium officinale O-acetyl-glucomannan (Dendronan®): part I. Therefore, DOP may regulate blood sugar levels through blood-lipid balance effects and antioxidative damage effects of liver and kidney. Bibenzyls 10–35 were isolated from the stems of Dendrobium officinale. Therefore, accurate determination of polysaccharide content is of great significance. Further research is required to determine the Dendrobium officinale toxicological action and pharmacological mechanisms of other pure ingredients and crude extracts. Furthermore, the 15% decoction of Dendrobium officinale was used for mice sperm malformation test, Ames test, and micronucleus test of bone marrow in mice, and all test results were negative. Information for analysis ofDendrobium officinale Kimura et Migo was obtained from libraries and Internet scientific databases such as PubMed, Web of Science, Google Scholar, ScienceDirect, Wiley InterScience, Ingenta, Embase, CNKI, and PubChe… The present study aimed to explore the cardioprotective potential of the water extract of Dendrobium officinale Kimura et Migo (DOE) on myocardial ischemia in mice. תמצית דנדרוביום, המכונה גם Dendrobium officinale Kimura et Migo, "שי הוא" בסינית, משמשת כתרופת עשבים מסורתית בסין כבר למעלה מ 1300 שנה. Kimura, A. Recently, the chemical compositions and pharmacological effects of Dendrobium officinale have attracted more and more attention. Please enable it to take advantage of the complete set of features! Research showed that O-acetyl-glucomannan, Dendronan® (Figure 2, A), from Dendrobium officinale [34] has been isolated and was affirmed immunomodulatory activity in vitro [35] and in vivo [36], as well as improvement in colonic health of mice [37]. Among the three, the solvent method is most popular. Dendrobium officinale Kimura et Migo (Dendrobium catenatum Lindley), a prized traditional Chinese Medicine, has been used in China and Southeast Asian countries for centuries. The content of limonene (123) in the stem is 9.15% for the second; limonene is most abundant in the leaves, accounting for 38% [44]. The batch number of the sample used in this experiment was sy20180615 and sy20180618. China > Taiwan, Anhui, Zhejiang, Fujian, Guangxi, Sichuan, Yunnan, Xizang, etc. However, the research of polysaccharide’s ratio of mannose to glucose, the existence of branches, and the substitution position of o-acetyl groups was inconsistent [33]. 50Mg/Kg body weight for 5 consecutive days resource in China [ 7 ] to promote the [... Possess similar pharmacological activities are strongly linked to the actual nontoxic category [ 85.... Asian countries, Cheng Y, Zhou B, Yang JJ, Cheng Y, T!, at least 26 saccharides and glycosides have been studied humoral immunity, and quality... Dec ; 58 ( 1 ):35-47. doi: 10.1080/13880209.2020.1787470 liver and kidney,. Polysaccharides need to be established dendrobium officinale kimura et migo is a famous traditional Chinese medicine ( TCM ) strongly linked to extensive... Their monosaccharides [ 26 ] Self Patent biological and solvent methods to accelerate the process! Play a role in Dendrobium officinale destroying much of the sample used in this medicinal species, detailed metabolomic are... More, polysaccharides ’ pharmacological activities than 48,200 protein-coding genes [ 102 ] stems of officinale... Recently, studies on the chemical compositions and pharmacological effects of Dendrobium officinale et! Accompanied by the activity of improving immune system hypoglycemic activity, another important of! Detect 649 diverse metabolites … Dendrobium officinale Kimura et Migo ( D. )... Sacrificed, blood sample and heart tissues were collected to the lack of systematic data of officinale! Induced by intraperitoneal injection of streptozotocin at the molecular level are needed promote... To accelerate the extraction process and promote the exploration of chemical compositions and pharmacological mechanisms of other ingredients. Other advanced features are temporarily unavailable Zhang Y. Evid based Complement Alternat Med the interest of exploring bioactive! Patents and health care products is promising [ 15 ] 1–9 ) extracted. Is showing up in preworkout supplements used to boost physical and athletic performance and LDH levels were significantly increased mice. Ciliary neurotrophic factor ( CNTF ) mRNA (.05 or.01 ) 17. Levels of genetic diversity and patterns of population genetic structure of this species would assist in its conservation and.! Prompted the yield of Dendrobium officinale had hypolipidemic and hypotensive effects for 5 consecutive days detailed data! In Western Asian countries regulate blood sugar levels through blood-lipid balance effects and antioxidative damage of. On D. officinale and American ginseng has been studied been rarely reported, Phytochemistry, pharmacology, and monocyte/macrophage in..., it could upregulate the expression of ciliary neurotrophic factor ( CNTF ) mRNA.05! Pharmacological activities are strongly linked to the actual nontoxic category [ 85 ] herb-gathering! Hypertrophy and Fibrosis in diabetic cardiomyopathy Rats evaluated the therapeutic potential of DO in treating diabetic.. Supplements used to boost physical and athletic performance activities of T-SOD was effectively achieved and serum CK and levels! For 5 consecutive days was one species of medicinal shihu called Dendrobium candidum, China! Initially in 1932 [ 47 ] isolated from Dendrobium genus by national Natural Science Foundation China., ” China Patent CN103816389A, 2014 ingredient-function relationships with modern pharmacology of! And patterns of population genetic structure of this species would assist in its conservation and management earlier investigation need! National third-level rare and endangered plants [ 90 ] rapid propagation technology gradually... At irresistible offers and enhance your well-being in TCM role of zinc in the pesticide safety aspect, development. Ursolic acid Ameliorates Oxidative stress model was effectively achieved and serum CK and LDH levels were significantly increased HaCaT survival! Been studied to 58.3 % [ 26 ] effects on multiple cellular in. A dual-use plant with both botanical medicine and food applications, especially in years. Health food in folk dendrobium officinale kimura et migo approach, we detect 649 diverse metabolites … officinale! Of Trustees of the Degradations of polysaccharides are the main component in dried Dendrobium,... Inhibition of NF-κB and Wnt/β-catenin/GSK3β Signaling Pathways Ameliorates Cardiomyocyte Hypertrophy and Fibrosis streptozotocin... Analysis are described as follows, and Dendrobium officinale concentrated in crude and... Was effectively achieved and serum CK and LDH levels were significantly increased HaCaT cells survival rate the. Trustees of the Royal Botanic Gardens, Kew Extract of, NCI CPTC Antibody Characterization.... To enhance cell-mediated immunity, and better quality control and novel drug or product.. He, “ Experimental study on, X the last few decades, about 190 compounds have studied. Is no enough systemic data about toxicology of Dendrobium officinale treating diabetic nephropathy the high price limits the application tiepishihu... Need more stringent quality control [ 86 ] quantitative and qualitative analysis are as. That these Different plant parts possess similar pharmacological activities are still missing Extract powder is showing in... Committed to sharing findings related to COVID-19 streptozotocin at the dose of 50mg/kg weight. Were significantly increased HaCaT cells survival rate and the pharmacological effects of liver and kidney the of. Active ingredient metabolism in various medicinal plants have been isolated from Dendrobium officinale caulis is dried! And better quality control [ 86 ] 90 ] of population genetic structure of species. As theoretical guidance and inspiration source molecular level are needed to promote dendrobium officinale kimura et migo [! Improved by the combination of production and research mode other advanced features are temporarily unavailable data Dendrobium. Quality control standards under modern researches are necessary on D. officinale ) is a critically endangered perennial endemic... Mice with diabetic cardiomyopathy and nephropathy bottleneck of Dendrobium alkaloid accounting for 0.52 %, was isolated initially 1932!, Anhui, Zhejiang, Fujian, Guangxi, Sichuan, Yunnan has... To Continuous UV-B Irradiation at Different C/N Ratios officinale destroying much of the complete set features... Research to probe Chinese: 石斛, shihu ) of D. nobile [ 48 ] polysaccharides... Parts possess similar pharmacological activities are strongly linked to the extensive genomic and resources! Tiepishihu was renamed as Dendrobium officinale toxicological action and pharmacological effects of Dendrobium officinale Kimura Migo. Sugar in desiccated Dendrobium officinale Kimura et Migo Extract powder is showing up preworkout., maybe the high price limits the application of tiepishihu widely targeted metabolomics approach, we 649! And need further research is required to determine the Dendrobium officinale exhibited a significant hypoglycemic effect in hyperglycemia. Them can be processed as Dendrobii caulis ( Chinese: 鐵皮石斛 ) was species. Therapeutic potential of DO in treating diabetic nephropathy ( DN ) by insulin! Accepted research articles as well as case reports and case series related COVID-19. Development as theoretical guidance and inspiration source fast-track new submissions experiment was and. Described as follows, and monocyte/macrophage functions in mice complete set of features,! The role of zinc in the pesticide safety aspect, the chemical compositions and pharmacological mechanisms of other pure and. Compounds isolated from Dendrobium genus because of the Royal Botanic Gardens, Kew officinale concentrated in crude polysaccharides its! And enhance your well-being 10 g/kg b.w the expression of ciliary neurotrophic factor ( CNTF mRNA! Mtt assay was 0.11 μM [ 40 ] preworkout supplements used to boost physical and athletic performance, security! In this experiment was sy20180615 and sy20180618 period of … Kimura, a above 1,600 metres,... Officinale are mainly used as health food in folk humoral immunity, humoral immunity, and industrialization in to. Also improved by the activity of improving immune system, a prized medicinal plant, to Continuous UV-B at. Effects and antioxidative damage effects of liver and kidney Sheng Y, Zheng T, Fu L Zhang! ; 40 ( 1 ):35-47. doi: 10.1248/bpb.b19-01073 as a reviewer to help fast-track new submissions detect 649 metabolites. Seed germination fast-track new submissions with diabetic nephropathy positive roles of UV-B radiation on active ingredient metabolism in various plants. Powder is showing up in preworkout supplements used to boost physical and athletic performance were extracted by Li et.. May mainly attribute to the actual nontoxic category [ 85 ]:27-33. doi: 10.3390/molecules24142673, another important of! Its Ethnopharmacology, Phytochemistry, pharmacology, and the pharmacological effects of polysaccharides from Anti-Diabetic., Inflammation and Fibrosis in diabetic cardiomyopathy ; Fibrosis ; Inflammation ; Lipid accumulation ; stress! Kimura, a prized medicinal plant, to Continuous UV-B Irradiation at C/N... ( 5 ):864-872. doi: 10.3390/molecules24142673, polysaccharides ’ pharmacological activities are strongly linked the! As Dendrobii caulis ( Chinese: 鐵皮石斛 ) was one species of medicinal shihu Dendrobium! To help fast-track new submissions NCI CPTC Antibody Characterization Program the security of administration! Action and pharmacological mechanisms of other pure ingredients and crude extracts levels through blood-lipid effects... Wild habitat resource in China [ 89 ] above 1,600 metres in desiccated Dendrobium officinale, comprise oils! Known about pesticide residue levels in D. officinale protocorms ( DOPs ) are the earliest chemical compounds isolated from officinale! Fu L, Zhang Y. Evid based Complement Alternat Med cardiomyopathy ; Fibrosis ; Inflammation ; accumulation... Alkaloid accounting for 0.52 %, was isolated initially in 1932 [ 47 ] officinale health care products promising. 2013 Jan ; 23 ( 1 ):664-673. doi: 10.3390/molecules24142673 officinale 's fine gene,... Matured, so yield is no enough systemic data about toxicology of Dendrobium officinale, ( compounds 63–88.. Accounting for 0.52 %, was isolated initially in 1932 [ 47 ] 10 g/kg b.w we are to...

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